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yfmR [2019-02-28 16:38:20]
similar to [SW|ABC transporter] (ATP-binding protein)
product
[SW|ABC transporter] (ATP-binding protein)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.4|Unknown ABC transporters]Gene
Coordinates
809,557 → 811,446
The protein
Catalyzed reaction/ biological activity
a paraloguous protein from ''E. coli'' (EttA) gates [SW|ribosome] entry into the translation elongation cycle [Pubmed|24389465,24389466]Protein family
[SW|ABC transporter] family (according to UniProt)[SW|ABCF ATPase subfamily] [pubmed|30597160]Paralogous protein(s)
[protein|1F56D3275386BB54A774BFA045C09E36D1268471|YdiF], [protein|2F79DB15D359A127C2D833CC0465E18E1725F539|YkpA], [protein|47B644F334A0BD501E77A198A61CE0F22BAB3E5E|YfmM] Structure
[PDB|3J5S] (EttA from E. coli, 36% identity) [pubmed|24389465][PDB|4FIN] (EttA from E. coli, 36% identity) [pubmed|24389466]Expression and Regulation
Operons
genes
[gene|F69F15198ACF8A8347C450EEC09F000EECEDEC41|yfmR]
description
[pubmed|22383849]
view in new tabBiological materials
Mutant
MGNA-C234 (yfmR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2232 NBRP B. subtilis, Japan]BKE07370 (Δ[gene|F69F15198ACF8A8347C450EEC09F000EECEDEC41|yfmR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE07370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGTTCCTATCAATCCTC, downstream forward: _UP4_TAAAAAGCGTGGCCGCAGCABKK07370 (Δ[gene|F69F15198ACF8A8347C450EEC09F000EECEDEC41|yfmR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK07370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGTTCCTATCAATCCTC, downstream forward: _UP4_TAAAAAGCGTGGCCGCAGCAReferences
Reviews
Original publications
10092453,24389466,24389465,27006457